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Main Data
Author: Charles J. Hackett, Donald A. Harn
Editor: Charles J. Hackett, Donald A. Harn Jr
Title: Vaccine Adjuvants
Publisher: Humana Press
ISBN/ISSN: 9781592599707
Edition: 1
Price: CHF 197.10
Publication date: 01/01/2007
Content
Category: Medizin & Pharmazie
Language: English
Technical Data
Pages: 284
Kopierschutz: DRM
Geräte: PC/MAC/eReader/Tablet
Formate: PDF
Table of contents
A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use. The focus is on specific receptor-ligand interactions, including the molecular features needed for a compound to possess adjuvant activity. The critical interface zone between the innate and adaptive immune systems is also analyzed to show how adjuvants exert their effects on T- and B-cell activation. Additional chapters address the possibility of tailoring adjuvants to yield optimally safe and effective responses.