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Autor: John Stone
Herausgeber: John H. Stone
Titel: & Myths in Rheumatology
Verlag: Springer-Verlag
ISBN/ISSN: 9781848009349
Auflage: 1
Preis : CHF 104.70
Erscheinungsdatum:
Inhalt
Kategorie: Medizin & Pharmazie
Sprache: English
Technische Daten
Seiten: 493
Kopierschutz: DRM
Geräte: PC/MAC/eReader/Tablet
Formate: PDF
Inhaltsangabe
Important strides have been made in understanding the pathophysiologic basis of many inflammatory conditions in recent years, but rheumatology remains a discipline in which diagnosis is rooted in the medical history skillfully extracted from the patient, the careful physical examination, and the discriminating use of laboratory tests and imaging. Moreover, selection of the most appropriate therapy for patients with rheumatic diseases also remains heavily reliant upon clinical experience. Medical disciplines such as rheumatology that depend significantly upon clinical wisdom are prone to the development of systems of 'Pearls' and 'Myths,' related to the diseases they call their own, a 'Pearl' being a nugget of truth about the diagnosis or treatment of a particular disease that has been gained by dint of clinical experience and a 'Myth' being a commonly held belief that influences the practice of many clinicians - but is false. This book will pool together the clinical wisdom of seasoned, expert rheumatologists who participate in the care of patients with autoimmune diseases, systemic inflammatory disorders, and all other rheumatic conditions.
Inhaltsverzeichnis
Preface5
Contents8
Contributors11
Chapter 118
Rheumatoid Arthritis18
1.1 Overview of Rheumatoid Arthritis18
1.1.1 Diagnosis18
1.1.2 Clinical Features18
1.1.3 Rheumatoid Arthritis Mimickers20
1.1.4 Serological Features and Radiology22
1.1.5 Risk Factors23
1.1.6 Disease Assessment23
1.1.7 Treatment24
1.1.7.1 Treatment Strategy24
1.1.7.2 Glucocorticoids, Methotrexate, and Conventional DMARDs24
1.1.7.3 Biologic Agents26
1.1.8 Co-Morbidities and Adverse Effects27
1.2 Immunizations in RA28
References28
Chapter 231
Rheumatoid Vasculitis31
2.1 Overview of Rheumatoid Vasculitis31
References37
Chapter 339
Adult-Onset Stills Disease39
References42
Chapter 443
Juvenile Idiopathic Arthritis43
4.1 Overview of Juvenile Idiopathic Arthritis43
References47
Chapter 549
Monogenic Autoinflammatory Syndromes49
5.1 Overview of the Monogenic Autoinflammatory Syndromes49
5.1.1 Familial Mediterranean Fever49
5.1.2 Tumor Necrosis Factor Receptor-Associated Periodic Syndrome (TRAPS)54
5.1.3 Hyper Immunoglobulin D and Periodic Fever Syndrome55
5.1.4 Cryopyrin-Associated Periodic Syndromes56
5.1.5 Chronic Recurrent Multifocal Osteomyelitis59
5.1.6 PAPA60
5.1.7 Cherubism61
References62
Chapter 666
Juvenile Spondyloarthropathy66
6.1 Overview66
References70
Chapter 772
Ankylosing Spondylitis72
7.1 Overview of Ankylosing Spondylitis72
References79
Chapter 881
Psoriatic Arthritis81
8.1 Overview of Psoriatic Arthritis81
References84
Chapter 986
Reactive Arthritis86
9.1 Overview of Reactive Arthritis86
References89
Chapter 1090
Systemic Sclerosis (Scleroderma) and Raynauds Phenomenon90
10.1 Overview of Systemic Sclerosis90
10.1.1 Raynauds Phenomenon and Digital Ischemia90
10.1.2 Diagnosis93
10.1.3 Autoantibodies and Disease Phenotypes93
10.1.4 Skin Disease96
10.1.5 Gastrointestinal Involvement97
10.1.6 Interstitial Lung Disease98
10.1.7 Pulmonary Arterial Hypertension101
10.1.8 Cardiac Disease103
10.1.9 Scleroderma Renal Crisis103
10.1.10 Musculoskeletal Manifestations104
10.1.11 Peripheral Neuropathy in SSc106
References106
Chapter 11109
Nephrogenic Systemic Fibrosis and Other Scleroderma Mimickers109
11.1 Overview of Nephrogenic Systemic Fibrosis and Other Scleroderma Mimickers109
11.2 Localized Scleroderma115
11.3 Morphea115
11.4 Scleromyxedema116
11.5 Eosinophilic Fasciitis117
References117
Chapter 12119
Sjögrens Syndrome119
12.1 Overview of Sjögrens Syndrome119
12.2 Classification and Epidemiology119
12.3 Pathogenesis121
12.4 Sicca Features121
12.4.1 Ocular Manifestations121
12.4.2 Oral Manifestations123
12.5 Parotid and Submandibular Involvement127
12.6 Extraglandular Involvement128
12.7 Laboratory Findings134
12.8 Immunological Assays135
12.9 Differential Diagnosis136
12.10 Prognosis and Outcome137
12.11 Systemic Treatment138
References138
Chapter 13143
Systemic Lupus Erythematosus143
13.1 Overview of Systemic Lupus Erythematosus143
13.2 Diagnosis143
13.3 Clinical Features145
13.4 Cutaneous Lupus148
13.5 Lupus Nephritis157
13.6 Central Nervous System Lupus158
13.7 General Management Points160
13.8 Treatment164
References167
Chapter 14172
Pediatric Systemic Lupus Erythematosus172
References176
Chapter 15179
Mixed Connective Tissue Disease179
Overview of Mixed Connective Tissue Disease179
References182
Chapter 16183
The Antiphospholipid Syndrome183
16.1 Overview of the Antiphospholipid Syndrome183
16.2 Risk Factors for Thrombosis in APS185
References189
Chapter 17191
Pregnancy in the Rheumatic Diseases191
17.1 Overview of Pregnancy in the Rheumatic Diseases